週次 |
日期 |
單元主題 |
第1週 |
9/16 |
Introduction.
Bio-inorganic chemistry versus inorganic biochemistry.
Important metals in biochemistry.
Important issues in bio-inorganic chemistry.
X-ray spectroscopy. XANES and EXAFS. |
第2週 |
9/23 |
X-ray spectroscopy. XANES and EXAFS. |
第3週 |
9/30 |
Electronic spectroscopy of copper centers. Ligand-to-metal charge transitions. Blue copper proteins. |
第4週 |
10/7 |
EPR spectroscopy of CuII |
第5週 |
10/14 |
Binuclear and trinuclear copper proteins |
第6週 |
10/21 |
Hemes and heme proteins. Myoblobin, hemoglobin; cytochrome c. |
第7週 |
10/28 |
Electronic, EPR and Raman spectra of heme proteins.
Cytochrome c peroxidase; horseradish peroxidase; cytochrome P450. |
第9週 |
11/11 |
Non-heme iron proteins.
Hemerythrin; ribonucleotide reductase; soluble methane monooxygenase. |
第10週 |
11/18 |
Iron sulfur clusters. Magnetic susceptibility. Mossbauer spectroscopy. |
第11週 |
11/25 |
Copper methane monooxygenase. Tricopper clusters.
C-H ativation |
第12週 |
12/2 |
Nickel/iron hydrogenases.
Photosynthesis. |
第13週 |
12/9 |
Photo-oxidation of water.
Oxygen-evolving complex.
Manganese EPR. |
第14週 |
12/16 |
Cytochrome c oxidase.
Electron transfer, dioxygen chemistry, and redox-linked proton pumping.
Cytochrome bc1.
Bacterial oxidases.
NADH dehydrogenase. |
第15週 |
12/23 |
Nitrogen fixation.
Structure of nitrogenase. |
第16週 |
12/30 |
NO,NO]2-andSO3]2- reductases. |
第17週 |
1/6 |
Long-range electron transfer in chemistry and biology. |
第18週 |
1/13 |
Final examination |